Example sentences for: camkii

How can you use “camkii” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have previously reported that retinal CaMKII mRNA, protein and enzyme activity (localized in the somas of amacrine cells and ganglion cells and in the inner plexifom layer) but not PKCα (localized in bipolar cells) are increased in the rdta mouse [ 34].

  • The Wnt/Ca 2+pathway has been shown to increase intracellular Ca 2+levels in zebrafish embryos [ 4 ] and to activate PKC and CamKII in Xenopus embryos [ 5 6 ] as well as in human melanomas [ 7 ] . Moreover, it may activate Cdc42 [ 8 ] and JNK [ 9 ] . It is important to emphasize that whether Wnts activate distinct responses and likely pathways is context-dependent, and thus in other contexts a given Wnt may activate another pathway.

  • Thus, enhanced phosphorylation by CaMKII may be involved in the altered levels of NMDA-receptor subunits observed here, but this remains to be tested.

  • While stimulation of PKC activity may decrease CaMKII binding to the NMDA receptor complex [ 56], there is no change in the level of PKC in the rdta mice [ 34].

  • The NR2 subunits of the NMDA receptor contain serine residues that can be phosphorylated by either CaMKII or PKC [ 53, 54, 55].


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