Example sentences for: calgranulin

How can you use “calgranulin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Finally, activation of macrophages results in the upregulation of the expression of molecules with lytic activity, such as calgranulin and grancalcin.

  • Different functional subsets of genes were identified that included those for several chemokines (GRO-1, MIG, MCP-1, MCP-3, MIP1-α, MIP-β, PARC, IL-8), cytokine receptors (C-CR-1, IL-R, IL-1R antagonist, IL-2Rβ, transforming growth factor-β receptor (TGFβR), IFNγR α chain), adhesion molecules associated with mononuclear cell migration (CD62L, VCAM-1, CD64, CD29), cytotoxic proteins in granules produced by activated monocytes (grancalcin and calgranulin) and several genes associated with IFN-γ activity, such as HLA class II molecules and IFN-regulatory or responsive genes such as those for MxA, MxB and IRF-1.

  • The results of this study suggest that IL-2 administration induces inflammation at the tumor site, with three predominant secondary effects: activation of antigen-presenting monocytes; a massive production of chemoattractants that may recruit other immune cells to the tumor site, among which are the chemokines MIG and PARC specific for T cells; and the activation of lytic mechanisms ascribable to monocytes (calgranulin, grancalcin) and NK cells (for example, NKG5, NK4) (Figure 8).


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