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Example sentences for: cagg
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The Neo 3' splice site contains a potential branch point sequence, and the sequence (CAGG) across the intron-exon boundary is optimal according to the scanning model of 3' splice site selection [ 54 55 ] . The Neo site differs from the typical 3' splice site in that it lacks a polypyrimidine tract; however, this feature is often missing from alternative splice sites [ 56 ] . Both the A of the branch point and the intron-terminal AG dinucleotide are considered invariant; therefore, one may be able to enhance the mutagenic efficiency of U3Neo vectors by altering these nucleotides.