Words similar to bxpc-

Example sentences for: bxpc-

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In the SMAD4 deleted BxPC-3 cells, TGFβ 1 resulted in phosphorylation of SMAD2/3, but the activated SMAD proteins were retained in the cytoplasmatic fraction (Figure 9).
Linking of the TGFβ-R pathway to the Ras/MAPK pathway is dependent on a functional SMAD4 gene product, because TGFβ 1 induced gene expression and activation of Ras and ERK1/2 is attenuated by the TGFβ-RII blocking antibody only in SMAD4 wild type cells, whereas in the SMAD4 deleted BxPC-3 cells, no such influence was observable.
BxPC-3 cells were stimulated with 10 nM of mature TGFβ 1 for 6 hours.
We incubated BxPC-3 cells with mature TGFβ 1 and observed an association on the cytoskeleton connected with integrin α V β 6 and activation of p125 FAK(Figure 4).
TGFβ 1 stimulation of these cells acvtivated p21Ras and MAPK ERK1/2, upregulated c-fos, c-jun/AP1, p21/WAF1 and p27 expression, and resulted a decrease of PCNA, similar to its actions in BxPC-3 cells.