Example sentences for: bxpc-

How can you use “bxpc-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Preincubation of the cells with the MEK1 inhibitor PD98059 curbed the TGFβ 1 -induced regulation of these genes as well, indicating the involvement of the MAP kinase pathway in TGFβ 1 signaling in BxPC-3 cells.

  • BxPC-3 cells were stimulated with 10 nM of mature TGFβ 1 for 6 hours.

  • In order to generalize the integrin mediated TGFβ 1 -pathway identified in the SMAD4 deleted pancreatic tumor cell line BxPC-3, we investigated TGFβ 1 signaling in the cervical carcinoma cell line HeLa and the mammary carcinoma cell lines MCF-7 and MDA-MB-231, harboring a wildtype SMAD4-gene.

  • TGFβ 1 stimulation of these cells acvtivated p21Ras and MAPK ERK1/2, upregulated c-fos, c-jun/AP1, p21/WAF1 and p27 expression, and resulted a decrease of PCNA, similar to its actions in BxPC-3 cells.

  • Preincubation with a TGFβ-RII blocking antibody attenuated the TGFβ 1 induced pattern, contrary to SMAD 4 deleted BxPC-3 cells.


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