Example sentences for: butaprost

How can you use “butaprost” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cells transfected with the vector alone demonstrated no significant increase in cAMP in response to butaprost free acid.

  • This mRNA expression pattern is similar to that of the EP 2 in the mouse [ 5 21 ] . PGE 2 has been reported to stimulate cAMP formation in many tissues, including intestine, microdissected renal tubule segments, and uterus via butaprost sensitive and insensitive receptors [ 14 26 27 28 29 ] . The mRNA expression results are consistent with these functional studies and suggest that the EP 2 receptor plays important roles in mediating PGE2 stimulated cAMP generation in these tissues [ 14 21 26 27 28 29 30 31 32 33 ] .

  • Furthermore, the EP 2 selective agonists butaprost free acid and AH13205 competed for [ 3H]PGE 2 binding with K i values of 3-7 μM and 3-4 μM, respectively, suggesting this receptor is the rabbit EP 2 receptor [ 20 21 ] .

  • Finally, the EP 2 selective agonist butaprost free acid dose-dependently stimulated cAMP generation in COS-1 cells transfected with the rabbit EP 2 receptor.

  • Incubation of EP 2 -transfected COS1 cells with butaprost free acid produced a concentration-dependent increase in cAMP accumulation with an EC 50 of 480 nM (Fig.


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