Words similar to butaprost

Example sentences for: butaprost

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Incubation of EP 2 -transfected COS1 cells with butaprost free acid produced a concentration-dependent increase in cAMP accumulation with an EC 50 of 480 nM (Fig.
Following this medium containing varying amounts of butaprost free acid was added to each well for 5 minutes.
This mRNA expression pattern is similar to that of the EP 2 in the mouse [ 5 21 ] . PGE 2 has been reported to stimulate cAMP formation in many tissues, including intestine, microdissected renal tubule segments, and uterus via butaprost sensitive and insensitive receptors [ 14 26 27 28 29 ] . The mRNA expression results are consistent with these functional studies and suggest that the EP 2 receptor plays important roles in mediating PGE2 stimulated cAMP generation in these tissues [ 14 21 26 27 28 29 30 31 32 33 ] .
Finally, the EP 2 selective agonist butaprost free acid dose-dependently stimulated cAMP generation in COS-1 cells transfected with the rabbit EP 2 receptor.
2 , PGF 2α , iloprost, misoprostol and sulprostone suggest it is not an EP 1 , EP 3 or IP receptor [ 2 3 ] . As demonstrated for the EP 2 receptor in other species [ 6 20 21 ] , butaprost free acid and AH 13205, two synthetic PG agonists with selectivity for the EP 2 subtype, efficiently and dose dependently compete for [ 3H] PGE 2 binding to this newly cloned rabbit receptor.