Example sentences for: butaprost

How can you use “butaprost” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The expression of EP2 receptor mRNA in medullary collecting duct is distinct from functional studies in the cortical collecting duct where butaprost had no functional effect [ 17 18 ] . These data suggest a possible unique role for the EP2 receptor in the medullary collecting duct as opposed to cortical collecting duct.

  • This mRNA expression pattern is similar to that of the EP 2 in the mouse [ 5 21 ] . PGE 2 has been reported to stimulate cAMP formation in many tissues, including intestine, microdissected renal tubule segments, and uterus via butaprost sensitive and insensitive receptors [ 14 26 27 28 29 ] . The mRNA expression results are consistent with these functional studies and suggest that the EP 2 receptor plays important roles in mediating PGE2 stimulated cAMP generation in these tissues [ 14 21 26 27 28 29 30 31 32 33 ] .

  • 2 , PGF 2α , iloprost, misoprostol and sulprostone suggest it is not an EP 1 , EP 3 or IP receptor [ 2 3 ] . As demonstrated for the EP 2 receptor in other species [ 6 20 21 ] , butaprost free acid and AH 13205, two synthetic PG agonists with selectivity for the EP 2 subtype, efficiently and dose dependently compete for [ 3H] PGE 2 binding to this newly cloned rabbit receptor.

  • Incubation of EP 2 -transfected COS1 cells with butaprost free acid produced a concentration-dependent increase in cAMP accumulation with an EC 50 of 480 nM (Fig.

  • Following this medium containing varying amounts of butaprost free acid was added to each well for 5 minutes.


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