Words similar to butait
Example sentences for: butait
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Chemical libraries can be screened for the ability to displace ButaIT leading to the discovery of better pesticides.
The neurotoxin P2 (35 ammo acids), another short toxin and a structural homologue of short insectotoxin II and 15, shows toxicity towards Sarcophaga falculata and crustaceans [ 26 ] . Chlorotoxin, isolated from Leiurus quinquestriatus haebraeus, shows Cl -channel-blocking activity and causes paralysis due to the inhibition of structurally related anion channels such as the extrajunctional channels of arthropod muscles [ 11 ] . It has also been reported that the short insectotoxin I5A may act on a "glutamate receptor of the postsynaptic membrane" [ 22 ] . Although no specific experimental evidence is available on the mode of action of ButaIT, it is assumed that ButaIT exerts similar ion channel blocking activity as that of other short insect toxins.
Considering the high degree of sequence similarity, it is presumed that ButaIT will have a similar 3-D structure to that of other short toxins.
When expressed in baculovirus system as a biopesticide scorpion toxins offer the advantage of faster kill without chemical insecticides [ 13 ] . Although the safety of recombinant baculoviruses is less of a concern ButaIT offers an extra level of safety as a recombinant biopesticide due to its specificity to tobacco budworm ion channels.
An examination of multiple sequence alignment with known insect toxins using BLAST search [ 28 ] revealed that ButaIT toxin shows considerable homology (Fig.
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