Words similar to bulky

Example sentences for: bulky

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The conserved basic residue interacts with the carboxylate group of the acidic substrate, while the bulky or aromatic residue located carboxy-terminal to the basic one forms the base of the cleft that holds this substrate molecule (Figure 2).
By contrast, ATP would likely not depend on the accessibility of the same hydrophobic cavity and is therefore probably not affected by the incorporation of a bulky methionine side chain [25].
The sixth position after the conserved basic residue is invariably occupied by a bulky residue that is either arginine (in AlkB) or phenylalanine or tryptophan in all other members of this fold [ 8, 9, 10] (Figure 1).
Thus, they concluded that by moving the bulky fluorophore to the end of vasotocin, and not altering an amino acid involved in binding and activation of the vasotocin receptor minimized the reduction in biological activity of the probes.
These include 7 hydrophobic residues, two sets of symmetrically positioned small (mostly glycine) and polar (mostly aspartate) residues preceding strands 3 and 6, respectively, and at least three other small residues, two polar residues and two bulky residues (Fig.