Words similar to bulky
Example sentences for: bulky
How can you use “bulky” in a sentence? Here are some example sentences to help you improve your vocabulary:
When he forgets the eye and the body and tries to appeal to the mind; when he blinds you with too-vivid zebra juxtaposed with too-vivid leopard so you can't see the dress; or when he overburdens the feminine torso with a short, floppy, bulky hoop skirt apparently made of hugely printed pastel silk curtains from a Las Vegas hotel room, topped by a short, bulky blue denim jacket with big brass buttons, then he starts looking too French, and by that I mean, theoretical.
I found them bulky, and their primary benefit seemed to come from the heat retention qualities of the neoprene.
By contrast, ATP would likely not depend on the accessibility of the same hydrophobic cavity and is therefore probably not affected by the incorporation of a bulky methionine side chain [25].
Thus, large amino acid residues in the CLF of a PKS that makes a 16-carbon chain were replaced by less bulky residues found in one that builds a 20-carbon chain, and the chain length of the product increased as expected.
predicted that Phe158 and Ile 164 form hydrophobic interactions with bulky substituents on the substrate, suggesting that the loss of these residues would only affect binding of substrates with large aromatic substituents [ 37 ] . In the modeling studies on CcrA [ 42 ] , Asn233 was predicted to interact with the β-lactam carbonyl on substrate, and mutagenesis studies have supported this prediction [ 43 ] . Although Asn233 is sequence conserved in L1 [ 35 ] , it is located 14Å away from the modeled position of the β-lactam carbonyl and was predicted not to play a role in substrate binding to L1 [ 37 ] . On the other hand, the substrate-binding model predicted that Tyr228 was in position to offer a hydrogen bond to the β-lactam carbonyl and participate in an oxyanion hole that was proposed to form as the substrate was hydrolyzed [ 37 ] . By using the crystal structure and modeling studies on L1, Ullah et al.
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