Words similar to bulkier

Example sentences for: bulkier

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In order to illustrate how, based on our models, a high affinity ligand can be rationally designed to be specific for beta2-containing nAChR subtypes, we searched a database of over 200,000 compounds (ChemDiv Inc., San Diego, CA), for alpha4-beta2 ligand candidates presenting a functional group close to Ala 135 of the beta2 subunit, hoping that such functional group could not accommodate the bulkier Leu 135 of beta4 (Figure 4- Top).