Words similar to bridging
Example sentences for: bridging
How can you use “bridging” in a sentence? Here are some example sentences to help you improve your vocabulary:
roughly divide the gp120 three-dimensional structure into outer (β9-β19 and β22-β24) and inner (N-α1, β4-β8, and α5-C) domains joined by a bridging sheet (β2, β3, β20, and β21) [ 44].
Bridging PCR (BPCR) is a combination of two processes, a recombination between two template sequences and an amplification of the recombinant template.
Phosphorothioate analogs 6b and 12b that preserve the α-β bridging oxygen but substitute carbon for the β phosphorus, achieving 65 to 75-fold binding advantages over AppppA, are expected to be critical for cell biological characterization.
… The Indian achievement is a combination of lightness and gravitas, of bridging the gap between the highbrow and the middlebrow, and rediscovering for itself the inextricable link between the body, mind and soul."
Efforts to solve the crystal structure of one of the metallo-β-lactamases with a bound substrate molecule have failed, most likely due to the high activity of the enzymes towards all β-lactam containing antibiotics [ 37 54 ] . Therefore, computational studies have been used extensively to study substrate binding, the role of the Zn(II) ions in catalysis, the protonation state of the active site, and inhibitor binding [ 37 42 55 56 57 58 59 ] . All of the substrate binding models have made assumptions before the substrate was docked into the active site [ 37 42 ] , and some of these assumptions have been shown to be invalid for certain substrates [ 43 ] . With L1, two key assumptions were made: (1) the bridging hydroxide functions as the nucleophile during catalysis and (2) Zn 1 coordinates the β-lactam carbonyl [ 37 ] . With these assumptions and after energy minimizations, Ser224 was predicted to hydrogen bond to the substrate carboxylate [ 37 ] , reminiscent of the role predicted for Lys224 in CcrA [ 42 ] . Ullah et al.
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