Example sentences for: brca

How can you use “brca” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although there is debate regarding the level of cancer risk associated with mutations in BRCA1 and the significance of the lack of mutations in sporadic tumors, it is possible that alterations in the function of BRCA1 may occur by mechanisms other than mutation, leading to an underestimation of risk when it is calculated solely on the basis of mutational analysis.

  • In summary, our findings suggest a possible novel mechanism by which the amino-terminal of BRCA1 suppresses apoptosis and facilitates DNA repair in human ovarian surface epithelial cells.

  • A frameshift mutation in the amino-terminal of the BRCA1 gene disrupts the RING domain and all domains after it.

  • Analysis of DNA synthesis in the mutant embryos indicated that cell proliferation was impaired, suggesting that BRCA1 may paradoxically play a positive role in the regulation of embryonic cell growth [ 29].

  • BRCA1 -F 5'-TCAGCTTGACACAGGTTTGG-3' (676-695 bp)


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