Example sentences for: brca

How can you use “brca” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The BRCA1 gene encodes a 220-kDa nuclear phosphoprotein that is regulated in response to DNA damaging agents [ 5, 6, 7] and in response to estrogen-induced growth [ 8, 9, 10, 11].

  • To test the hypothesis that BRCA1 may play a role in the regulation of ovarian tumor cell death as well as in the inhibition of ovarian cell proliferation.

  • Decreased BRCA1 levels appeared to affect the ability of BG-1 cells to arrest growth or die in the absence of estrogenic growth-inducing conditions.

  • This cell line, which expresses wild-type BRCA1, is estrogen responsive, and withdrawal of estrogen results in eventual cell death.

  • One hundred thousand cells were separated by 5% SDS-PAGE, transferred by wet-transfer to PVDF membrane, and blotted as described above using monoclonal antibody specific for the N-terminus of BRCA1 (Oncogene Boston, MA).


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