Example sentences for: brca

How can you use “brca” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, the BG-1 control clone (NEO) was unable to form colonies (fewer than one colony per 10 4cells plated) in agar without the addition of estrogen, whereas the BG-1 antisense BRCA1 clone was able to form soft agar colonies in estrogen depleted conditions (10 ± 2.9 colonies per 10 4cells plated).

  • Whole cell lysate (50 μg) was loaded onto a 6% sodium dodecyl sulfate-polyacrylamide gel electrophoresis gel, transferred to nitrocellulose, and hybridized with an anti-BRCA1 (Ab-1; Oncogene Research, Cambridge, MA, USA) antibody as previously described [ 10].

  • Three independent BRCA1 antisense-infected cultures demonstrated a resistance to cell death induced by withdrawal from estrogen over a 6- to 20-day period (Fig.

  • The multivariate Cox regression analysis showed that promoter methylation is an independent predictor of outcome for BRCA1 (3-fold risk) and MGMT (2.

  • The present studies show that reduction in BRCA1 levels, using an antisense retroviral vector in the estrogen dependent BG-1 ovarian carcinoma cell line, contributes to confirmation of the hypothesis that BRCA1 plays a pivotal role in the balance between cell death and cell proliferation.


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