Words similar to blebs

Example sentences for: blebs

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In the continuous presence of MTX, blebs continue to swell and in many cases seem to disappear as they dilate and extend out of the focal plane.
However, during MTX-induced cytolysis, as indicated by the release of LDH, the membrane blebs actually exhibit a dramatic increase in diameter.
Although the cellular mechanisms remain poorly defined, it is now clear that zeiosis is associated with apoptotic cell death (for review [ 24 30 ] ). In static images, the morphological changes associated with apoptosis appear as membrane blebs covering the surface of the cells [ 31 32 33 ] . However, time-lapse images reveal that blebs protrude and retract in a dynamic fashion, a hallmark of zeiosis [ 22 23 ] . Dynamic membrane blebbing appears to involve a dramatic change in the cytoskeleton and may be induced by a caspase-3-mediated cleavage of ROCK-I, a Rho-activated serine/threonine kinase known to stimulate actinomycin-based contractions [ 31 32 33 ] . A similar profile can be seen in the videos of MTX-induced cell death in the presence of U73343 ( Files 2 and 3 ). The cells first lose adhesion to the coverslip, retract and roundup.
Interestingly, the videos show several examples of blebs forming on the surface of pre-existing blebs during the dilation phase.
As previously reported, blebs form during the first phase of dye uptake, whereas rather dramatic bleb dilation is seen during the cytolysis phase of rapid dye uptake.