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Example sentences for: blebbing

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blue arrows ). The time-lapse movie of this experiment revealed that these detached cells were actually undergoing a novel type of membrane blebbing called zeiosis (see Additional File 2).
Keratocytes situated within the 20-40 μm of the upper stroma, demonstrated various pathological changes including cytoplasm vacuolization and blebbing, with formation of cellular fragments (fig 3).
This is followed by zeiotic membrane blebbing.
Although the cellular mechanisms remain poorly defined, it is now clear that zeiosis is associated with apoptotic cell death (for review [ 24 30 ] ). In static images, the morphological changes associated with apoptosis appear as membrane blebs covering the surface of the cells [ 31 32 33 ] . However, time-lapse images reveal that blebs protrude and retract in a dynamic fashion, a hallmark of zeiosis [ 22 23 ] . Dynamic membrane blebbing appears to involve a dramatic change in the cytoskeleton and may be induced by a caspase-3-mediated cleavage of ROCK-I, a Rho-activated serine/threonine kinase known to stimulate actinomycin-based contractions [ 31 32 33 ] . A similar profile can be seen in the videos of MTX-induced cell death in the presence of U73343 ( Files 2 and 3 ). The cells first lose adhesion to the coverslip, retract and roundup.
As seen in Fig 7and the video, dramatic membrane blebbing and ethidium uptake is observed 25 min after re-addition of Ca 2+to the bath.