Words similar to biphenyls
Example sentences for: biphenyls
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On one hand, there is increasing and rather convincing observational and experimental data underscoring the beneficial effects of marine fish consumption on fetal growth and gestation [ 1 2 3 ] . On the other hand, consumption of environmentally contaminated fish has been associated with decrements in gestation and birth weight in some studies [ 4 5 6 ] . Animal evidence suggests that Rhesus monkeys, rats and mice exposed to polychlorinated biphenyls (PCBs) in utero have reductions in length of gestation and growth [ 7 8 9 ] . The results from accidental environmental exposures also report adverse effects on birth size and ectodermal manifestations among fetuses to various polyhalogenated hydrocarbons [ 10 11 ] . One occupational study has reported a negative relation between PCB exposure and infant birth weight, which no longer remained significant after adjusting for gestation and other variables related to birth weight [ 12 ] . Results from a birth cohort study in the Faroe Islands, a community with a high intake of marine fish, whale meat and blubber, supported a relation between marine fatty acids and diminished birth weight for gestation, but the effects were not attributed to the mercury or PCB exposure [ 13 ] .
PCB, polychlorinated biphenyls
Epidemics of overt toxicity following widespread environmental contamination from commercial toxins heralded the discovery of children's enhanced vulnerability to lead, methyl mercury, polychlorinated biphenyls (PCBs), and tobacco [1,2,3,4,5] (Box 1).
Contamination of the Great Lakes has led to the bioaccumulation of polychlorinated biphenyls (PCBs) in fish, particularly the larger predator species prized by sport-fishers [ 1 2 3 ] . These compounds are synthetic organochlorines (OC) that, along with dichlorodiphenyl-dichloroethene (DDE), comprise the bulk of OC residues found in human tissues [ 4 ] , and some of the highest body burdens of PCBs in humans are found among fish consumers [ 5 6 7 8 ] . Consumption of these contaminated Great Lakes fish has been associated with several adverse reproductive outcomes including shortened menstrual cycle [ 9 ] , reduced fecundability [ 10 11 ] , reduced neonatal size [ 12 ] , and neurologic disorders [ 13 14 15 ] .
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