Words similar to biphenyls
Example sentences for: biphenyls
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Contamination of the Great Lakes has led to the bioaccumulation of polychlorinated biphenyls (PCBs) in fish, particularly the larger predator species prized by sport-fishers [ 1 2 3 ] . These compounds are synthetic organochlorines (OC) that, along with dichlorodiphenyl-dichloroethene (DDE), comprise the bulk of OC residues found in human tissues [ 4 ] , and some of the highest body burdens of PCBs in humans are found among fish consumers [ 5 6 7 8 ] . Consumption of these contaminated Great Lakes fish has been associated with several adverse reproductive outcomes including shortened menstrual cycle [ 9 ] , reduced fecundability [ 10 11 ] , reduced neonatal size [ 12 ] , and neurologic disorders [ 13 14 15 ] .
Epidemics of overt toxicity following widespread environmental contamination from commercial toxins heralded the discovery of children's enhanced vulnerability to lead, methyl mercury, polychlorinated biphenyls (PCBs), and tobacco [1,2,3,4,5] (Box 1).
PCB, polychlorinated biphenyls
On one hand, there is increasing and rather convincing observational and experimental data underscoring the beneficial effects of marine fish consumption on fetal growth and gestation [ 1 2 3 ] . On the other hand, consumption of environmentally contaminated fish has been associated with decrements in gestation and birth weight in some studies [ 4 5 6 ] . Animal evidence suggests that Rhesus monkeys, rats and mice exposed to polychlorinated biphenyls (PCBs) in utero have reductions in length of gestation and growth [ 7 8 9 ] . The results from accidental environmental exposures also report adverse effects on birth size and ectodermal manifestations among fetuses to various polyhalogenated hydrocarbons [ 10 11 ] . One occupational study has reported a negative relation between PCB exposure and infant birth weight, which no longer remained significant after adjusting for gestation and other variables related to birth weight [ 12 ] . Results from a birth cohort study in the Faroe Islands, a community with a high intake of marine fish, whale meat and blubber, supported a relation between marine fatty acids and diminished birth weight for gestation, but the effects were not attributed to the mercury or PCB exposure [ 13 ] .
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