Example sentences for: biosynthesis

How can you use “biosynthesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The resulting field of ‘combinatorial biosynthesis’ of ‘unnatural natural products’ has been given added urgency by the rise of multidrug-resistant pathogens, of which MRSA (methicillin-resistant

  • Brown, unpublished data), and inhibition of ergosterol biosynthesis [ 35 ] . This data has been log-transformed (base 2), and each experimental condition has been median normalized.

  • These changes in flowering time are similar to what was observed for the maize bm mutants [ 12 ] . If the correlation between flowering dynamics and cell wall biosynthesis were spurious, mutations affecting cell wall composition in evolutionarily related species with different flower morphology would not show association with flowering dynamics.

  • Human Fhit [ 14 ] and the S. cerevisiae Fhit homolog [ 13 ] , which was called Aph1 but is here termed Hnt2 under nomenclature aproved by the Saccharomyces Genome Database, cleave ApppA more readily while Aph1, the S. pombe homolog, cleaves AppppA more readily [ 20 ] . Consistent with the ApppA hydrolase activity of purified Fhit protein, most cancer cell lines that are Fhit negative at the protein level have higher levels of ApppA than cell lines that are Fhit positive [ 21 ] . Nonetheless, the actual concentrations of dinucleoside polyphosphates were submicromolar in every cell culture sample [ 21 ] and thus, under the reported culture conditions, the measured dinucleoside polyphosphates would not be expected to occupy the Fhit active site substantially [ 19 ] . Dinucleoside polyphosphate levels were measured in adenine-requiring S. cerevisiae strains before or after disruption of the Fhit-homologous HNT2 gene [ 13 ] and in adenine-requiring S. pombe strains as a function of disruption and overexpression of the Fhit-homologous aph1 gene [ 22 ] . Recently, it was observed that diadenosine polyphosphates undergo a divalent cation-dependent conformational change that might mediate their biosynthesis, catabolism or signaling properties [ 23 ] .

  • Immuno-histochemical analysis of mouse embryos shows that ALDH1A1 expression occurs primarily in cranial tissues, while ALDH1A2 expression occurs primarily in trunk tissue [ 17 ] . In addition, the targeted knockout of the ALDH1A2 gene in mice results in a significant decrease in retinoic acid biosynthesis and early embryo death [ 18 ] .


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