Example sentences for: biogenesis

How can you use “biogenesis” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have used a genetic strategy to identify factors required for proper NPC biogenesis.

  • We predicted that factors required for total NPC biogenesis would be essential, as functional NPCs are absolutely required for nuclear transport.

  • Genes involved in histidine biosynthesis (for example HIS4 and HIS5 ) clustered with other genes involved in amino-acid synthesis (cluster 2 and cluster 80) but also with genes required for adenine biogenesis (cluster 1), in agreement with the roles of these gene products in both histidine and purine metabolism [ 32, 33].

  • In fact, Hurt and coworkers have recently demonstrated the in vitro assembly of a Nup subcomplex from entirely recombinant proteins [ 20 ] . Given the structural and functional similarities between vertebrate and yeast NPCs and the insertion of both into a pre-existing NEs, it is likely that NPC biogenesis occurs via a similar mechanism in all organisms.

  • The phenotypes observed in sec13 and sec23 mutants might indicate that COPII vesicles and/or a vesicular biogenesis step is required for NPC formation; however, there are at least two indirect mechanisms by which NPC structure may be changed in these mutants.


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