Words similar to binds
Example sentences for: binds
How can you use “binds” in a sentence? Here are some example sentences to help you improve your vocabulary:
i for analog 2 suggests that analog 2 binds weakly to Y152 while lerisetron and analog 1 bind more tightly.
While TNFα binds equally well to both receptors, the majority of biologic responses attributed to TNF are mediated via TNFR1 although there is evidence that activation of TNFR2 is responsible for some adverse effects of TNFα [ 19 20 21 22 23 24 ] . Thus, the differential regulation of these two receptors may require drugs that specifically target either TNFR1 or TNFR2 allowing therapeutic efficacy without the expected toxicity profile.
The crystal structures of the metallo-β-lactamases reveal a complex and far-reaching hydrogen-bonding network around the metal binding sites, and disruption of this network is predicted to affect metal binding [ 37 42 44 45 48 49 62 63 ] . With all of the mutants described here except the S224K mutant, each mutant binds wild-type or near-wild-type levels of Zn(II) after purification.
We suggest that species D2 corresponds to the conformation that releases ADP as an intermediate product and species D1 corresponds to the conformation that binds ADP as a substrate.
C/EBPα binds to and activates transcription of the gene promoter for the p21 inhibitor of cyclin-dependent kinase (CDK) [ 37 ] . This led to speculation that p21 gene activation may contribute to cell cycle arrest by C/EBPα [ 37 ] . Similarly, suppression of mitotic growth during adipocyte differentiation was associated with C/EBPα activation of the promoters of gadd45 (growth arrest and DNA damage-inducible gene 45), gas2 and gas3 (growth arrest-associated genes 2 and 3) [ 5 6 38 39 ] . However, C/EBPα mutants defective in DNA binding still blocked proliferation [ 25 33 ] . This suggested that direct promoter activation was unnecessary, or redundant, for C/EBPα proliferation arrest [ 18 ] .
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