Example sentences for: bind

How can you use “bind” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The precursor of heparin-binding EGF-like growth factor (proHB-EGF) is found on a wide variety of cell surfaces and is present in numerous tissue types [ 1 ] . Previously in our laboratory, we cloned the cDNA encoding proHB-EGF from monkey Vero cells and identified this cell-surface molecule as a receptor for diphtheria toxin (DT) [ 2 ] . The predicted amino acid sequence was shown to be identical to that of the cell surface-expressed precursor of human heparin-binding EGF-like growth factor (proHB-EGF) [ 3 4 ] . The derived amino acid sequence revealed a signal sequence (residues 1-23), an extracellular domain (residues 24-159), a transmembrane domain (residues 160-184), and a carboxyl terminal cytoplasmic domain (residues 185-208) [ 2 ] . Proteolytic processing of the proHB-EGF occurs on the cell surface and results in the release of mature HB-EGF (mHB-EGF) (residues 63-148) [ 5 ] . The mature/soluble HB-EGF is a member of the EGF family of growth factors that includes amphiregulin, epidermal growth factor, and transforming growth factor a [ 6 ] . Mature HB-EGF released from the cell surface is mitogenic and is able to bind to the EGF receptor [ 3 ] . Membrane-bound proHB-EGF has juxtacrine growth factor activity [ 7 ] and also acts as a DT receptor [ 2 8 ] .

  • In contrast, chromatin remodelling factors like SWI/SNF, ISW1, BRG1 facilitate transcription from chromatinised templates in the presence of ATP [ 18 ] . However, these factors do not bind to specific DNA sequences.

  • With these additions, we can represent the hypothetical action of 'K-channel blockers' that bind to and inhibit ATP-sensitive potassium channels so that increased intracellular Ca 2+activates intranuclear calmodulin.

  • Even if the two condensation reactions, in very general terms, could be considered a reversal of the polysaccharide hydrolysis reaction, there is no indication that polysaccharide hydrolases could bind and hydrolyze ATP, and the multiple alignment of the MJ1477 family did not include any conserved signatures typical of potential phosphate-binding loops (Figure 1).

  • Molecular chaperones bind to nascent proteins in the endoplasmic reticulum (ER), promote proper protein folding, and prevent the aggregation of nonnative and misfolded proteins.


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