Example sentences for: bhlh

How can you use “bhlh” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Some E-box or bHLH binding factors activate the same genes as SREBP-1.

  • The promoters of a subset of genes in the stress cDNA collection are enriched in G-box and TGA motifs, suggesting that they may be regulated by these bZIP and bHLH transcription factors.

  • SREBPs are critically important basic helix-loop helix (bHLH) transcription factors activated in response to variations in intracellular cholesterol levels that induce transcription of genes with sterol regulatory element (SRE) and E-box containing promoters.

  • It has been shown that the differentiation of pillar cells depends on activation of Fgfr3 [ 26 ] by FGF's, probably Fgf8, a factor produced by developing and mature inner hair cells [ 18 27 ] . The formation of supporting cells also appears to depend on the proper expression of various bHLH factors such as Hes 1 and 5 which appear to be regulated by the Notch signaling pathway [ 17 28 29 ] . It is possible that the apparent inability of fibers to extend along outer hair cells is related to the lack of differentiation of supporting cells in the absence of mature hair cells.

  • Cell processes that EF-hand proteins may be involved in are suggested by domains found in transcription or translation proteins including elongation factors and the bHLH domain found in transcription factors.


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