Example sentences for: bhlh
How can you use “bhlh” in a sentence? Here are some example sentences to help you improve your vocabulary:
PIF3 belongs to a plant-specific family of basic helix-loop-helix (bHLH)-domain- containing proteins that, in addition to the bHLH domain, have an uncharacterized conserved domain at the amino terminus present in single or duplicate copies (L.M.I.
The bZIP transcription factors are important in the regulation of genes activated by light, UV radiation, pathogen attacks, elicitors, wounding, abscisic acid (ABA) treatment, and SA treatment [ 47 71 74 75 76 77 78 79 80 81 ] . We identified two basic zipper (bZIP) transcription factors and basic helix-loop-helix (bHLH) transcription factors in the stress cDNA collection.
A specific complex that formed a Dnase I footprint (-306 to -265) in the cAMP-responsive region of the RIIβ promoter in granulosa cells [ 18 ] , covers a consensus E-box (CACGTG) known to bind helix-loop-helix (bHLH) transcription factors.
It has been shown that the differentiation of pillar cells depends on activation of Fgfr3 [ 26 ] by FGF's, probably Fgf8, a factor produced by developing and mature inner hair cells [ 18 27 ] . The formation of supporting cells also appears to depend on the proper expression of various bHLH factors such as Hes 1 and 5 which appear to be regulated by the Notch signaling pathway [ 17 28 29 ] . It is possible that the apparent inability of fibers to extend along outer hair cells is related to the lack of differentiation of supporting cells in the absence of mature hair cells.
In mammals, the positive elements are two basic helix-loop-helix (bHLH) PAS-domain-containing transcription factors, CLOCK and BMAL1, that form heterodimers that can drive the transcription of three period ( per ) genes per1-3 and two cryptochromes ( cry1,2 ). PER1,2 and CRY1,2 proteins suppress CLOCK:BMAL1-mediated transcription thereby forming the negative elements in the feedback loop.
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