Example sentences for: bfgf

How can you use “bfgf” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The addition of bFGF, VEGF, or PMA to the monolayers ECs induced cellular elongation over a period of 8 to 24 hr.

  • Oligonucleotide primers were purchased from Sigma-Genosys; recombinant human VEGF (VEGF 165), bFGF, anti-VEGF (MAB293), and anti-MMP1 (MAB900) from R&D Systems; adult human serum-AB, from Gemini Bioproducts; and bovine skin-derived type I collagen, from Cohesion Inc.

  • The biologic activity of the endostatin encoded in the adenoviral vector was determined through the bFGF simulated HUVEC proliferation assay.

  • bFGF: Fibrobast Growth Factor b

  • Mediators known to activate ECs include inflammatory cytokines, growth factors such as VEGF/VPF and basic fibroblast growth factor (bFGF), extracellular matrix (ECM) proteins such as collagen and fibronectin, and proteases such as MMPs [ 1 2 ] . In vitro and in vivo assays indicate that VEGF signaling promotes increased permeability, cell migration, proliferation, and differentiation, functioning through two EC-specific tyrosine kinase receptor such as Kinase domain receptor (KDR) [ 1 2 3 ] . In the majority of solid tumors, VEGF is upregulated in response to hypoxia, inducing the expression of pro-angiogenic genes that promote tumor angiogenesis, growth and eventual metastasis [ 3 4 5 ] . The expression of both positive and negative factors must be tightly and specifically regulated in a coordinated manner.


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