Words similar to basolateral
Example sentences for: basolateral
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They found a decrease in total (apical + basolateral) bile acid uptake compared to normal controls [ 12 ] and hypothesized that bile acid malabsorption in cystic fibrosis was due to a primary mucosal defect although they had not specifically studied apical, Na +-dependent absorption.
We found, however, that the polarized cells secreted Gro-1 in response to exposure to wild-type bacteria at either the apical or basolateral surface, with most of the Gro-1 secreted from the basolateral membrane (Figure 9b).
Surprisingly, the apical surface appeared to be most sensitive to the presence of bacteria, but this could be explained by the fact that the membrane supporting the basolateral cell surface reduced the amount of surface area available for receptor expression.
Calcium extrusion at the basolateral membrane is an active process involving a Ca-ATPase that may also be affected by vitamin D status [ 8 ] . However, although it has been known for more than 20 years that the rate of Ca transport across the intestinal brush border membrane can be increased by 1,25-dihydroxyvitamin D [ 9 ] , the identity of the calcium transport protein involved in Ca influx has not been ascertained.
Of course, a more widespread perturbation of ion channel regulation in the absence of CFTR is also a possibility, as CFTR has been demonstrated to be a master regulator of such diverse proteins as the Na/K pump [ 41 ] , the basolateral Na/K/2Cl co-transporter [ 42 ] , and the inducible nitric oxide synthase [ 43 ] .
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