Example sentences for: bak

How can you use “bak” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Bak migrates to the mitochondrial outer membrane where it generates transmembrane pores; Bax induces the opening of the mitochondrial permeability transition pores.

  • Activated or truncated Bid (tBid) in turn activates Bak and Bax.

  • Most studies suggest that supplemental posterior fixation using pedicle screw-rod construct improves stability in all direction, and also levels off any difference in stability between stand alone interbody implant constructs [ 4 16 ] . In a cadaver spine study Rathonyi et al [ 17 ] reported that stand alone BAK cages failed to provide stability in extension and axial rotation.

  • 1and 2) and was shown to destabilize lipid membranes in vitro (along with Bax) by increasing the permeabilization of artificial liposomes [ 25 26 ] . Therefore it is possible that tBid can bind to the cardiolipin rich contact site membranes and destabilize them by inducing Bax or Bak to oligomerize.

  • Recent work has shown that the Bcl-2 family regulates mitochondrial homeostasis during apoptosis [ 1 ] . Pro-apoptotic members, including Bax, Bak, Bid, and Bim, promote the release of death-inducing proteins, such as cytochrome c [ 2 3 ] , smac [ 4 ] , and endonuclease G [ 5 ] , from mitochondria while anti-apoptotic members, such as Bcl-2 and Bcl-X L , inhibit this release.


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