Words similar to baecs

Example sentences for: baecs

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MTX had no effect on BAECs incubated in Ca 2+-free buffer.
Since U73343 can rapidly block and reverse the increase in [Ca 2+] i induced by MTX, it seems likely that these compounds directly block the MTX-activated channels in BAECs, perhaps acting as pore blockers.
Thus, BAECs are particularly sensitive to the cytolytic effects of MTX.
Addition of MTX to fura-2 -loaded BAECs, suspended in a cuvette in normal Ca 2+-containing buffer at 37°C, produced a time-dependent increase in [Ca 2+] i (Fig 1, upper panel ). Addition of either U73122 or U73343, the inactive analog, ~3 min before MTX produced a concentration-dependent inhibition of the change in [Ca 2+] i . U73343 exhibited a 3-fold greater potency compared to U73122 (Fig 1, insets ). Since U73343 has no significant effect on PLC over the concentration range employed [ 14 25 26 27 ] , these results suggest that inhibition of the MTX-induced response is independent of PLC.
Fura-2-loaded BAECs were suspended in HBS, placed in a cuvette at 37°C, and the response to extracellular application of MTX was recorded as a function of time (Fig.