Words similar to ataxia

Example sentences for: ataxia

How can you use “ataxia” in a sentence? Here are some example sentences to help you improve your vocabulary:

Although the formation of intranuclear inclusions has not been observed in previous studies of Ras-related GTPases, it is a common feature of several neurodegenerative disorders where abnormal proteins containing poly-Gln tracts are synthesized as a result of CAG codon expansions [ 52 ] . Examples include Huntington's disease (huntingtin) [ 53 54 ] , spinocerebellar ataxia (SCA) types 1 and 3 (ataxin-1 and ataxin-3) [ 55 56 ] and dentatorubral-pallidoluysian atrophy (atrophin-1) [ 57 ] . These poly-Gln protein aggregates typically contain ubiquitin [ 58 ] and members of the Hsp70 chaperone family [ 59 ] , consistent with a proposed pathway for cellular clearance of toxic misfolded proteins.
This other half of iron homeostasis could also easily have a role in Friedreich's ataxia and X-linked sideroblastic anemia.
Lower copy numbers of this mutation (~ 70%) are associated with neuropathy, ataxia and retinitis pigmentosa (NARP) whereas high copy numbers (>90%) give rise to Leigh syndrome [ 15].
In these animals exon 3 and its splice acceptor were deleted, causing a rare intergenic transcript between Prion and Doppel to be highly upregulated and abnormally expressed in the brain, leading to late-onset ataxia and Purkinje cell degeneration [ 34 ] .
Such expansion of the polyQ domains in certain neuronal proteins could cause neurodegenerative disorders, e.g., Huntington's disease or several forms of ataxia.