Words similar to aspartic

Example sentences for: aspartic

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Most other myosins have a constitutively negatively charged amino acid, either aspartic acid (D) or glutamic acid (E) at this site.
CTX fragments derived from newly synthesised collagen are of the native peptide form ( L-aspartyl peptide [α L]), where the aspartic acid residue (D 1211) is on the L-enantiomeric form and is linked to the glycine residue (G 1212) through a peptide bond.
The structures identify a zinc ion chelated to the two histidines and the aspartic residue of the MPN + /JAMM sequence.
In L1, the residue at position 224 is a serine [ 35 ] , and the substrate-binding model for L1 predicts that this serine residue interacts with the carboxylate on substrate via a water molecule [ 37 ] . To test the proposed role of Ser224 in L1, serine was changed to an alanine (S224A), aspartic acid (S224D), and lysine (S224K), and these mutants were characterized using metal analyses, CD spectroscopy, steady-state kinetics, and pre-steady state kinetic studies.
Instead, we predict that the insertion of an aspartic acid into the active site at position 224 results in a change in the hydrogen bonding network in L1; this hydrogen bonding network is extensive in all metallo-β-lactamases that have been characterized crystallographically [ 37 42 44 45 48 49 62 63 ] . The N233D mutant also exhibited greatly reduced k cat values for biapenem and meropenem but not for imipenem or any of the other substrates tested.