Words similar to aspartic
Example sentences for: aspartic
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Instead, we predict that the insertion of an aspartic acid into the active site at position 224 results in a change in the hydrogen bonding network in L1; this hydrogen bonding network is extensive in all metallo-β-lactamases that have been characterized crystallographically [ 37 42 44 45 48 49 62 63 ] . The N233D mutant also exhibited greatly reduced k cat values for biapenem and meropenem but not for imipenem or any of the other substrates tested.
The Arabidopsis and other plant myosins all have aspartic acid, glutamic acid or glycine residue at this site, suggesting that they are not regulated by phosphorylation at this site.
CTX fragments derived from newly synthesised collagen are of the native peptide form ( L-aspartyl peptide [α L]), where the aspartic acid residue (D 1211) is on the L-enantiomeric form and is linked to the glycine residue (G 1212) through a peptide bond.
T1DM susceptibility in the NOD mouse is linked to I-A g7, the murine MHC class II gene that encodes a histidine at position 56 and a serine at position 57 in the β chain, in place of the more frequent proline 56β and aspartic acid 57β [ 3 ] . The development of diabetes is prevented in NOD.PD mice (which are NOD mice with I-A g7) that carry a β chain transgene with site-specific mutations that restore proline and aspartic acid at positions 56β and 57β, respectively [ 4 ] . Furthermore, because of the two amino acid changes in the additional (transgenic) MHC class II allele β chain in NOD.PD mice, NOD.PD mice recognize three additional peptide epitopes in the glutamic acid decarboxylase 65 (GAD65) autoantigen [ 5 ] .
The human immunodeficiency virus type 1 aspartic protease (HIV-1 PR) is an important enzyme due to its key role in viral maturation.