Words similar to aspartic
Example sentences for: aspartic
How can you use “aspartic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Most other myosins have a constitutively negatively charged amino acid, either aspartic acid (D) or glutamic acid (E) at this site.
[ 10 ] A vast series of pre-clinical and clinical studies have suggested 5-FU is a more active anti-tumor agent when modulated by a host of compounds including leucovorin, [ 11 12 13 ] methotrexate, [ 14 ] folinic acid, [ 15 16 ] N-phosphonacetyl-L-aspartic acid (PALA) [ 17 18 19 20 21 22 ] and recombinant interferon alfa-2a (IFNaα-2a).
T1DM susceptibility in the NOD mouse is linked to I-A g7, the murine MHC class II gene that encodes a histidine at position 56 and a serine at position 57 in the β chain, in place of the more frequent proline 56β and aspartic acid 57β [ 3 ] . The development of diabetes is prevented in NOD.PD mice (which are NOD mice with I-A g7) that carry a β chain transgene with site-specific mutations that restore proline and aspartic acid at positions 56β and 57β, respectively [ 4 ] . Furthermore, because of the two amino acid changes in the additional (transgenic) MHC class II allele β chain in NOD.PD mice, NOD.PD mice recognize three additional peptide epitopes in the glutamic acid decarboxylase 65 (GAD65) autoantigen [ 5 ] .
Mutation of Asp355 by asparagine (the non charged analog of aspartic acid), or by histidine or lysine (that have a positively charged side chain) or by alanine (neutral), inactivated PAI-1.
C-terminal to this region, all have one or more acidic domains consisting of a total of 17 to more than 100 aspartic acid and glutamic acid residues per molecule.
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