Words similar to aspartate
Example sentences for: aspartate
How can you use “aspartate” in a sentence? Here are some example sentences to help you improve your vocabulary:
A standard hematology profile was prepared, including white-blood-cell count with differential count, and a serum-chemistry profile was prepared, consisting of sodium, potassium, chloride, blood urea nitrogen, creatinine, glucose, phosphorus, total bilirubin, alkaline phosphatase, aspartate aminotransferase, alanine aminotransferase, albumin, uric acid, total protein, C-reactive protein (CRP), fibrinogen, and a microscopic urinalysis.
The residues in the MIDAS motifs lie on three closely apposed loops located on the upper edge of the β-sheet, where they form the metal-binding site, with oxygen atoms in the aspartate, serine and threonine residues coordinating the metal ion [ 9 ] . In integrin α2β1, which is a collagen receptor, the metal-binding site also binds the collagen ligand through the conserved glutamate in a GFOGER motif (O = hydroxyproline) completing the coordination sphere of the metal [ 28 ] . In vivo, the binding of collagen at this site appears to be regulated through a conformational shift in which the loops forming the MIDAS site change from a closed to an open conformation [ 29 30 31 ] . Other proteins containing a domain with all three MIDAS motifs include the D-subunit of magnesium chelatase [ 32 ] , Ca-activated chloride-channel protein [ 33 34 ] , nitrate reductase (accession AAC79447), and the D subunit of nitric oxide reductase (accession AAC45374).
The assembly of myosin II monomers into filaments is regulated by phosphorylation of its heavy chains at three threonine residues at the C-terminus of the tail [ 9 10 ] . Dephosphorylation of these threonines is a prerequisite of filament assembly, as confirmed by the phenotypes of a 3xAsp mutant, in which the three threonines are replaced by three aspartate residues (mimicking the phosphorylated state) [ 11 ] . In vitro the 3xAsp myosin II is severely impaired for filament assembly, and in vivo 3xAsp myosin II fails to assemble or localize to the cortical cytoskeleton.
Among these are broad-specificity aspartate aminotransferases with ability to function with aromatic amino acids.
Previously, the proteins were undetected by western analysis in purified maize bundle-sheath cells, using antibodies against Panicum maximum aspartate aminotransferase and Cucumis sativus alanine aminotransferase.
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