Words similar to aromatic
Example sentences for: aromatic
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Previous enzymological work had demonstrated the existence of five aminotransferases in P. aeruginosa that were capable of functioning as aromatic aminotransferases in vitro [ 35].
They include: (1) sulfate esters of polysaccharides {carrageenan [ 1 16 17 18 19 ] , cellulose sulfate [ 12 13 14 15 ] , and dextran or dextrin sulfate [ 1 2 3 4 5 6 7 8 9 10 11 ] }; (2) aryl sulfonates {poly(naphthalene sulfonate) [ 22 23 24 ] and poly(styrene-4-sulfonate) [ 20 21 ] }; and (3) aliphatic {Carbomer 974P/BufferGel [ 25 26 27 28 29 ] } and aromatic carboxylates {CAP [ 30 31 32 33 34 35 36 37 ] }. The anti-HIV-1 properties of these polymers are expected to depend on their complexation with virus proteins which is likely to occur mainly through the formation of salt linkages or ion pairs between oppositely charged groups on the polymers and virus proteins, respectively [ 56 ] . However, the anti-HIV-1 properties of these polymers may depend not only on their charge density, but also on the characteristics of their uncharged portions, which may be involved in hydrophobic and hydrogen bonding interactions which can elicit profound conformational changes in hydrophobic regions of proteins and cause disassembly of complex proteins consisting of subunits [ 57 ] . For these reasons it is not be expected that all anionic polymers, considered as anti-HIV-1 microbicides, would have similar biological activities.
The specifications for such structure include a nitrogen atom separated by two carbon atoms from an aromatic moiety and containing an electron donating substituent at the meta-position.
Thus, aromatic hydroxylation of such compounds at the ortho-position would form a catechol ring (Table 3, #12) and produce metabolites that are structural analogues to dopamine.
Biophore #8 features an aromatic residue that presumably binds to the hydrophobic pockets of the channel walls (e.g.
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