Words similar to aromatase
Example sentences for: aromatase
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Androgen stimulation of genital fibroblasts was carried out under two different culture conditions similar to those previously reported to produce induction of aromatase enzymatic activity in these cell lines [ 8 27 ] . In the first, cells were grown to confluence as described above using phenol-red-free DMEM F12 containing L-glutamine, 15 mM Hepes buffer, penicillin/streptomycin (Gibco) with 12.
However, brain aromatase and circulating plasma estradiol levels in male rats does not appear to be influenced by dietary phytoestrogens [ 22 41 51 ] . As the results from this research imply, phytoestrogens have considerable effects on hormonally sensitive parameters and their influence may be, in part, responsible for many reported sexual dimorphisms such as, the establishment and plasticity of sexually dimorphic brain structures like the sexually dimorphic nucleus of the preoptic area (SDN-POA) and the anteroventral periventricular nucleus (AVPV) [ 40 41 ] .
In learning and memory tasks, which require the use of visual spatial cues, males acquire and exhibit superior performance to females [ 13 14 15 16 17 18 19 20 ] . This sex difference in rats has been attributed to the hormonal influence of estrogen (presumably by way of its in situ conversion from testosterone by the aromatase enzyme in brain) [ 19 20 21 22 ] , and is observable morphologically in visually spatial critical brain areas (i.e.
An increase in the activity of aromatase induced locally could explain the drop in androgen levels and the increase in estrogens observed in patients with RA [ 38].
Although two previous reports have shown increases in aromatase enzymatic activity in genital skin fibroblasts treated with dihydrotestosterone (DHT) [ 8 27 ] , others have failed to observe changes in aromatase activity in response to androgen [ 28 ] . In agreement with our findings, Elmlinger
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