Example sentences for: arix

How can you use “arix” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Lastly, sporadic individuals with classic CFEOM were screened for ARIX mutations.

  • This finding is consistent with our prediction that, compared to ARIX, the genes mutated in CFEOM1 may have a more restricted function in the development of nIII and that their expression may actually be regulated by ARIX.

  • Thus far, this phenotype segregates as an autosomal recessive trait and maps to the FEOM2 locus on chromosome 11q13 [ 8 ] , and affected individuals carry homozygous mutations in ARIX [ 5 ] . ARIX encodes a homeodomain transcription factor required for nIII and nIV development in mice and zebrafish [ 22 23 ] . In families with CFEOM3, the CFEOM phenotype is variably expressed.

  • One is consistent with linkage to FEOM1 and not FEOM3 and, although consistent with linkage to FEOM2, ARIX mutations were not identified.

  • In addition, to further define the spectrum of human ARIX mutations, we identified all CFEOM1 families consistent with linkage to FEOM2 or sporadic individuals with classic CFEOM and determined that none harbored mutations in the ARIX gene.


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