Words similar to arix
Example sentences for: arix
How can you use “arix” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thus far, this phenotype segregates as an autosomal recessive trait and maps to the FEOM2 locus on chromosome 11q13 [ 8 ] , and affected individuals carry homozygous mutations in ARIX [ 5 ] . ARIX encodes a homeodomain transcription factor required for nIII and nIV development in mice and zebrafish [ 22 23 ] . In families with CFEOM3, the CFEOM phenotype is variably expressed.
ARIX mutation detection
Genomic DNA samples from affected member of pedigree BC and K and 5 sporadic individuals with classic CFEOM were used as templates to sequence the three ARIX exons and flanking introns.
ARIX, which encodes a transcription factor critical to nIII and nIV development in mice and zebrafish [ 22 23 ] , was recently identified as the FEOM2 gene mutated in affected members of CFEOM2 families [ 5 ] . It was unknown, however, if classic CFEOM may also result from mutations in this gene.
Lastly, sporadic individuals with classic CFEOM were screened for ARIX mutations.