Example sentences for: apv

How can you use “apv” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • If patients were antiretroviral-experienced, they had to be naïve to APV, have a plasma HIV-1 RNA >1000 copies/mL, show susceptibility to APV and ≥ 2 other antiretroviral drugs, and remain on their most recent treatment regimen until completion of the screening visit.

  • Reasons for premature withdrawal from treatment were also similar between the APV600/RTV and APV1200 arms, except for fewer patients in the APV600/RTV arm withdrawing due to protocol-defined virologic failure (1% vs 6%) (Table 1).

  • Thus, plasma APV levels well above the IC 50 s of most HIV isolates were most likely achieved in ESS40011.

  • The higher incidence of oral/perioral paresthesia in the APV1200 treatment arm was most likely due to the higher APV C max that occurs following APV1200 dosing compared with APV600/RTV BID dosing [ 17 ] . Although the incidence of headache has been shown to increase with higher APV C max values [ 18 ] , the incidence of this adverse event did not differ between treatment arms in this study.

  • GI adverse events reported in the APV600/RTV arm were possibly due to the addition of RTV to the regimen, or because the reduction in pill burden and, hence, in excipients was not great enough to improve GI tolerance.


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