Example sentences for: apcs

How can you use “apcs” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Apcs deficiency was however associated with markedly increased renal damage, suggesting that this gene may be involved in preventing pathological consequences of autoantibody production.

  • Stimulation of the various receptors expressed by T cells and APCs results in the activation of distinct and also redundant signal transduction pathways, and in the activation of distinct as well as redundant transcription factors.

  • In this issue of PLoS Biology , Marina Botto and her colleagues have tested this hypothesis by taking one of their knockout models for SLE, the serum amyloid P component deficient mouse ( Apcs −/− ) (Bygrave et al.

  • This group has published that Apcs −/− mice on a (129 × B6) genetic background develop a lupus-like disease, even after repeated backcrosses to B6 (Bickerstaff et al.

  • , genetically identical, except for the gene of interest), carrying the same 129 region on Chromosome 1, but expressing Apcs . Amazingly, no difference was found between the two strains regarding the production of autoantibodies, clearly eliminating Apcs deficiency as a mechanism for this autoimmune process.


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