Example sentences for: apc

How can you use “apc” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The primers used for methylated and unmethylated-specific PCR for genes RARB , TIMP3 , CDKN2A , p14 ARF , MGMT , DAPK , CDH1 , GSTP1 , APC promoter 1A, RB1 , MLH1 , TP73 , BRCA1 , FHIT , and HIC1 have been described previously http://pathology2.jhu.edu/pancreas/prim0425.htm#MSP; [ 34 35 36 37 ] . For additional genes, we designed the following gene-specific primers for methylated (MF and MR) and unmethylated (UF and UR) sequences according to Herman et al [ 33 ] :

  • The Min /+ model has received great favour because it contains a mutation in the Apc gene, which is homologous to the human adenomatous polyposis coli (APC) gene [ 23 ] . Defects in the APC tumour suppressor gene are thought to play a role in greater than 70% of all colorectal cancers and is responsible for inherited syndromes of polyposis (FAP and Gardner's) [ 24 25 ] . Furthermore, in humans the majority of colorectal cancers arise from adenomatous polyps [ 26 ] .

  • On the other hand, methylation of BRCA1 , APC , CDH1 , and TIMP3 genes did not correlate with expression levels.

  • 5 (BD Biosciences), tetramer–PE, and a panel of two or three different anti-VB monoclonal Abs labeled with fluorescein isothiocyanate, allophycocyanin (APC), or both.

  • The abnormal factor V that causes APC resistance was subsequently termed factor V Leiden.


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