Example sentences for: apc

How can you use “apc” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The Min /+ model has received great favour because it contains a mutation in the Apc gene, which is homologous to the human adenomatous polyposis coli (APC) gene [ 23 ] . Defects in the APC tumour suppressor gene are thought to play a role in greater than 70% of all colorectal cancers and is responsible for inherited syndromes of polyposis (FAP and Gardner's) [ 24 25 ] . Furthermore, in humans the majority of colorectal cancers arise from adenomatous polyps [ 26 ] .

  • Fluorescein fluorescence was detected through the FL-1 channel, APC fluorescence was assessed using the FL-4 channel, and data were acquired and analyzed using the CellQuest ®application on a Power Macintosh G3 computer.

  • The greatly increased incidence of medulloblastomas in patients inheriting mutations in the APC tumor suppressor gene suggests that activation of Wnt signaling could be sufficient in some cases to initiate medulloblastoma formation.

  • They showed APC1's affinity for Ca 2+and the potential for a Ca 2+-dependent conformational change.

  • APC = allophycocyanin; ARE = AU-rich element; CM = complete media; ELISA = enzyme-linked immunosorbent assay; FACS = fluorescence-activated cell sorting; FITC = fluorescein isothiocyanate; IL = interleukin; KLH = keyhole limpet hemocyanin; LPS = lipopolysaccharide; MESF = milliequivalents of soluble fluorescein; RPMI = Roswell Park Memorial Institute [medium]; RT-PCR = reverse transcriptase polymerase chain reaction; TNF = tumor necrosis factor; TNFR = TNF receptor; TTP = tristetraprolin; WBC = white blood cell.


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