Example sentences for: apaf-

How can you use “apaf-” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • They are: "Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3" (PMID: 9267021), a paper linked to APAF1; and "The ced-8 gene controls the timing of programmed cell death in C. elegans" (PMID: 10882128), a paper linked to XK.

  • Cytochrome c is then released from the mitochondria into the cytosol, where it interacts with downstream proapoptotic proteins such as Apaf-1 and caspase 9. Activation of these proteins further activates nucleases, such as caspase-activated DNase (CAD), which cause DNA fragmentation.


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