Words similar to antitumor
Example sentences for: antitumor
How can you use “antitumor” in a sentence? Here are some example sentences to help you improve your vocabulary:
It has been proposed that vitamin E may incorporate into cellular membranes by association of the tocopherol side chain with the polyenoic fatty acid residues in the membrane fatty acids [ 15 19 ] . This interaction may stabilize cell membranes by making highly unsaturated fatty acids less liable to peroxidation as well as by making highly unsaturated fatty acids less available for phospholipid hydrolysis by phospholipase [ 15 16 ] . The latter action may reduce mobilization of arachidonic acid (AA) from the membranes and in this way reduce the amount of AA available as a substrate to cyclooxygenase and/or lipoxygenase to produce eicosanoids with mitogenic and with inflammatory properties [ 17 20 ] . Other possible antitumor actions include: induction of apoptosis, interference with hormone production, modulation of cellular signaling and gene transcription, and induction of differentiation [ 4 21 22 23 24 ] .
d-Limonene, which comprises > 90% of citrus peel oil, has demonstrated chemopreventive activity against a variety of chemically induced rodent cancers [ 17 18 19 20 21 22 ] . Several mechanisms of action may account for the antitumor activities of d-limonene [ 23 24 25 ] . Among citrus bioflavonoids, hesperidin and naringin have been tested as potential chemopreventive agents [ 26 27 ] . In our previous studies, we showed that citrus peel use [ 28 ] and consumption of hot (strong) black tea [ 29 ] were each independently associated with reduced risk of skin SCC.
For instance, he says, “most active antitumor medicines have multiple mechanisms of action.
The observed antitumor activity of this sE dietary supplementation was an unexpected experimental result as sE was not previously reported to have antitumor activity although vitamin E may give modest protection against the risk of breast cancer [ 5 ] . Based on the observed antitumor activity of high dose sE in the diet, it became important to investigate if the sE supplement, when fed at such a high dose, was associated with the modification of the fatty acid composition of mitochondrial and microsomal membranes and if the sE was acting as an antioxidant or possibly a prooxidant in tumor and in host tissues.
It has been recently appreciated that sufficient concentrations of secreted IFNg may also induce susceptible tumors to express the MHCII molecules, potentially leading to increased direct contact with CD4+ T cells [ 3 ] . Even though some reports indicate that tumor sensitivity to IFNg is not required to elicit tumor regression [ 4 ] , it is conceivable that the IFNg-induced MHCII expression on tumor cells may boost the effector phase of antitumor responses through additional cytokine release or direct tumor eradication by CD4+ T cells.
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