Words similar to antithyroid

Example sentences for: antithyroid

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The drugs have been studied with relation to their effect in Graves' hyperthyroidism which, like psoriasis, is an autoimmune disorder [ 9 10 11 12 ] Antithyroid thioureylenes, of which propylthiouracil, methimazole and carbimazole are used in clinical practice, have known immunomodulatory properties [ 13 14 ] and, in the case of psoriasis, also have antiproliferative effects as demonstrated by their ability to produce a decline in markers of cellular proliferation such as proliferative cell nuclear antigen (PCNA) [ 15 ] .
We previously reported the effectiveness of thioureylene treatment in patients with plaque psoriasis [ 4 5 6 7 ] , a finding since confirmed by others [ 8 ] . The mechanism of action of antithyroid thioureylenes in psoriasis remains unclear.
[ 1 2 ] Treatment of the disease results in costs that range between 0.7 to more than 4 billion dollars annually in the US alone [ 3 ] . One of the most cost-effective forms of potential treatment for the disease is the use of antithyroid thioureylenes such a propylthiouracil.
The efficacy of antithyroid thioureylenes as agents in the treatment of plaque psoriasis is well established [ 4 5 7 8 ] The mechanism of action of these agents in psoriasis remains unclear.
Antithyroid peroxidase (anti-TPO) binding activity was determined by a radiobinding assay using Iodine 125labelled human recombinant thyroid peroxidase (Nichols Institute, San Juan Capistano, CA).