Words similar to antiretroviral-naïve
Example sentences for: antiretroviral-naïve
How can you use “antiretroviral-naïve” in a sentence? Here are some example sentences to help you improve your vocabulary:
The purpose of ESS40011 was to compare the efficacy, safety, and tolerability of APV 600 mg BID plus RTV 100 mg BID (APV600/RTV) to APV 1200 mg BID (APV1200) over 24 weeks in antiretroviral-naïve or -experienced HIV-infected patients who were receiving other background antiretroviral drugs.
Other beneficial features of the APV600/RTV regimen, such as improved dosing convenience and reduced pill burden, need to be factored into decision making when APV600/RTV is being considered by clinicians as a therapeutic option for the treatment of either antiretroviral-naïve or -experienced patients with HIV infection.
The proportion of antiretroviral-naïve patients who achieved HIV-1 RNA <200 copies/mL in the APV600/RTV arm was twice that for the APV1200 arm (63% vs 30%, P = 0.141).
The proportion of antiretroviral-naïve patients who achieved HIV-1 RNA <50 copies/mL was 47% (14/30) in the APV600/RTV arm and 20% (2/10) in the APV1200 arm ( P = 0.141), whereas the proportion of antiretroviral-experienced patients who achieved HIV-1 RNA <50 copies/mL was 34% (43/128) in the APV600/RTV arm and 21% (9/43) in the APV1200 arm ( P = 0.119) (ITT:M = F analysis).
In another study of APV600/RTV in antiretroviral-naïve patients, Arasteh et al [ 19 ] reported a higher proportion of patients achieving plasma HIV-1 RNA <50 copies/mL (75%) than in the present study, perhaps due to the use of only lamivudine and abacavir as background antiretroviral medication and to differences in their study population relative to ours.
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