Words similar to antiretroviral-experienced
Example sentences for: antiretroviral-experienced
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The proportion of antiretroviral-naïve patients who achieved HIV-1 RNA <50 copies/mL was 47% (14/30) in the APV600/RTV arm and 20% (2/10) in the APV1200 arm ( P = 0.141), whereas the proportion of antiretroviral-experienced patients who achieved HIV-1 RNA <50 copies/mL was 34% (43/128) in the APV600/RTV arm and 21% (9/43) in the APV1200 arm ( P = 0.119) (ITT:M = F analysis).
No significant differences were observed between the APV600/RTV and APV1200 treatment arms with respect to mean AAUCMB in HIV-1 RNA for the antiretroviral-experienced subgroup (-1.
The proportion of antiretroviral-experienced patients in the APV600/RTV treatment arm who achieved HIV-1 RNA <200 copies/mL at 24 weeks (58% [ITT:observed analysis]; 42% [ITT: M = F analysis]) was comparable to that reported in antiretroviral-experienced patients at 24 weeks in the studies by Schooley et al [ 20 ] (ESS40006 [PEARL]) (69% [ITT:observed analysis]), but much higher than that reported by Katlama et al [ 21 ] (31% [ITT: M = F analysis]).
No differences in virologic efficacy between treatment arms were evident in the antiretroviral-experienced subgroup (42% vs 40%, P = 0.859).
A total of 211 patients enrolled; they were predominantly male (87%), ethnically diverse (48% Caucasian, 37% African American, 14% Hispanic), and had a mean age of 42 years, median baseline HIV-1 RNA level of 4.33 log 10 copies/mL, and median baseline CD4+ cell count of 257 cells/mm 3. Most of the study population was antiretroviral-experienced (81%).
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