Words similar to antiretroviral-experienced
Example sentences for: antiretroviral-experienced
How can you use “antiretroviral-experienced” in a sentence? Here are some example sentences to help you improve your vocabulary:
The greater magnitude of virologic suppression in the study population as a whole with the APV600/RTV regimen was expected in view of the results of earlier clinical pharmacokinetic studies showing a >6-fold higher C min level with APV600/RTV BID compared with the APV1200 BID regimen [ 16 ] . Higher C min values achieved with RTV-boosting may be critical in treating antiretroviral-experienced patients, particularly those with HIV isolates having increased IC 50 values.
No differences in virologic efficacy between treatment arms were evident in the antiretroviral-experienced subgroup (42% vs 40%, P = 0.859).
The proportion of antiretroviral-experienced patients in the APV600/RTV treatment arm who achieved HIV-1 RNA <200 copies/mL at 24 weeks (58% [ITT:observed analysis]; 42% [ITT: M = F analysis]) was comparable to that reported in antiretroviral-experienced patients at 24 weeks in the studies by Schooley et al [ 20 ] (ESS40006 [PEARL]) (69% [ITT:observed analysis]), but much higher than that reported by Katlama et al [ 21 ] (31% [ITT: M = F analysis]).
In contrast, the proportions in antiretroviral-experienced patients were similar in the treatment arms in both analyses (ITT: M = F analysis: 42% [54/128] vs 40% [17/43], P = 0.859; ITT: observed analysis: 58% [54/93] vs 53% [17/32], P = 0.682).
It was lower in magnitude than the CD4+ cell count increases reported for APV600/RTV arm at 24 weeks in antiretroviral-experienced patients in ESS40006 [ 20 ] , and similar to that reported in heavily pre-treated patients by Katlama et al [ 21 ] in a patient population with comparable baseline disease characteristics (median HIV-1 RNA of 4.5 log 10 /mL and CD4+ count of 227 cells/mm 3).
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