Words similar to antipsychotic
Example sentences for: antipsychotic
How can you use “antipsychotic” in a sentence? Here are some example sentences to help you improve your vocabulary:
The odds ratio for both categorical measures of dependence was significantly higher with worse cognitive impairment, increasing with each detrimental point change in ADAS-cog or MMSE score, adjusting for age, gender and use of antipsychotic medication (Table 2).
Clozapine is a widely used atypical neuroleptic with affinity for multiple receptors, including dopamine, serotonin, alpha adrenergic, muscarinic and histaminergic receptors [ 1 2 ] . Although clozapine is effective in the treatment of schizophrenia refractory to traditional antipsychotic medication, it also has a number of significant side effects ranging from the potentially fatal but rare agranulocytosis to weight gain, constipation, seizures and urinary incontinence [ 3 ] . Urinary problems have been reported in the clinical literature with incontinence present in up to 44% of patients [ 4 ] and enuresis in 27% of patients [ 5 ] . Since clozapine has potent anti-muscarinic and anti-alpha adrenergic effects [ 2 ] , it has been proposed that peripheral effects on the lower urinary tract might be responsible for the micturition disturbances [ 6 ] . Incontinence has also been reported following therapy with other atypical neuroleptics such as risperidone [ 7 8 9 ] and recently, olanzapine [ 10 ] .
Atypical neuroleptics are useful in treating patients that are refractory to "traditional" antipsychotic medication and produce fewer extrapyramidal side effects.
A three-point difference in MMSE score was associated with an increase in the adjusted odds of requiring more than 12 hours of supervision of 43% at the time of the assessment; and if dependence is measured as level three or higher, the odds increase by 82%, even after adjusting for age, gender and use of antipsychotic medication.
This is consistent with other studies, which found that patients using antipsychotic agents [ 19 ] or displaying psychotic symptoms [ 1 19 20 21 ] are more likely to experience a faster functional decline.
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