Words similar to antiproliferative
Example sentences for: antiproliferative
How can you use “antiproliferative” in a sentence? Here are some example sentences to help you improve your vocabulary:
Based on its antiprogesterone activity, RU486 has been evaluated as a useful anticancer agent in organs sensitive to this hormone [ 4 ] . Although evidence was not conclusive in these studies, RU486 demonstrated a benefit to humans suffering from meningioma, breast cancer and uterine leiomyomata [ 4 ] . Several in vitro studies also demonstrated that RU486 induced antiproliferative effects against murine mammary tumors [ 5 ] as well as cultured human endometrial stromal and epithelial cells [ 6 7 ] .
It is well established that, besides the MHCII molecules, IFNg can induce susceptible tumors to upregulate the expression of MHC class I antigens [ 43 ] , tumor associated antigens [ 44 ] , costimulatory molecules [ 45 ] , and heat shock proteins [ 46 ] . In addition, IFNg may have antimetabolic and antiproliferative influence on certain types of tumor cells [ 47 ] . It has also been suggested that IFNg may cause responding tumor cells to secrete angiogenesis inhibitors [ 48 ] . As it is not known which of those IFNg effects are missing or restored by PMA in LS1034 cells, a thorough evaluation of the possible clinical implications of our in vitro findings is quite difficult.
The direct role of RARB in regulating gene expression and its retinoid-mediated antiproliferative, differentiative, immuno-modulatory, and apoptotic-inducing properties may offer a therapeutic target in the future for CC treatment [ 25 ] .
The drugs have been studied with relation to their effect in Graves' hyperthyroidism which, like psoriasis, is an autoimmune disorder [ 9 10 11 12 ] Antithyroid thioureylenes, of which propylthiouracil, methimazole and carbimazole are used in clinical practice, have known immunomodulatory properties [ 13 14 ] and, in the case of psoriasis, also have antiproliferative effects as demonstrated by their ability to produce a decline in markers of cellular proliferation such as proliferative cell nuclear antigen (PCNA) [ 15 ] .
The antiproliferative effects of RA have been recognized for many years.
Loading...