Words similar to antiproliferative
Example sentences for: antiproliferative
How can you use “antiproliferative” in a sentence? Here are some example sentences to help you improve your vocabulary:
The antiproliferative effects of RA have been recognized for many years.
Based on its antiprogesterone activity, RU486 has been evaluated as a useful anticancer agent in organs sensitive to this hormone [ 4 ] . Although evidence was not conclusive in these studies, RU486 demonstrated a benefit to humans suffering from meningioma, breast cancer and uterine leiomyomata [ 4 ] . Several in vitro studies also demonstrated that RU486 induced antiproliferative effects against murine mammary tumors [ 5 ] as well as cultured human endometrial stromal and epithelial cells [ 6 7 ] .
The antiproliferative effects of RA have been attributed to its inhibition of AP-1 transcriptional activity [ 13 ] . While the S77A RARα mutant has been shown to inhibit transactivation of RA response elements [ 7 ] , its effects on AP-1 activity have not been characterized.
The direct role of RARB in regulating gene expression and its retinoid-mediated antiproliferative, differentiative, immuno-modulatory, and apoptotic-inducing properties may offer a therapeutic target in the future for CC treatment [ 25 ] .
Laboratory investigations support the capability of citrus peel or its major constituents, d-limonene, and also the ability of tea extract or its constituents, tea polyphenols to reduce not only the incidence and tumor size of chemically-induced tumors at several sites [ 4 8 9 17 18 20 22 ] but also the growth of various tumor cells in culture [ 11 33 ] . Both d-limonene, representative of citrus peel, and tea polyphenols, representative of black tea, are known to impact antiproliferative effects, including apoptosis, on neoplastic cells [ 4 34 35 36 37 ] . Dietary d-limonene has been shown to be effective in the chemoprevention and chemotherapy of cancer.
Loading...