Example sentences for: antinociception

How can you use “antinociception” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Ligands acting at δ receptors can induce antinociception both spinally and supraspinally [ 10 11 12 ] , thus identifying ligands that activate δ opioid receptors and determining their physiochemical characteristics is essential to understanding opioid receptor pharmacology and physiology.

  • Phyllanthus urinaria plant was used by Caribs with other plants in a bath against bad luck (called 'piai') [ 66 ] . Pharmacological activities of various compounds in some species of Phyllanthus include analgesic, antiinflammatory, antilipoxigenase, antiallergic, nitrosamina blocker, aldose reductase inhibitor, antiviral, mitochondrial ATPase inhibitor, phosphodiesterase inhibitor and cyclooxigenase inhibitor [ 111 ] . Other activities are hepatoprotective, phosphorilase and tirosine kinase inhibitor, phospholipase A 2 inhibitor and increased the survival of hepatocellular carcinoma harbouring animals [ 54 111 113 112 ] . The compound with hepatoprotective activity is triacontanol [ 114 ] . Several compounds found in Phyllanthus species, like flavonoids (quercetin, rutin), tannins (geraniin, furosin), benzenoids (ethyl gallate, methyl gallate) and phytosterols showed antinociceptive effects in mice or multiple mechanisms of action [ 111 115 ] . The flavonoids also have anti-inflammatory properties [ 38 11 ] . The hydroalcoholic extracts of four Phyllanthus species were 2 - 6 fold more active in causing antinociception than aspirin depending on the route of administration and the pain model used [ 115 ] . Phyllanthus amarus has antioxidant properties, reverses chromosomal alterations induced by genotoxic agents and has anticancer activity [ 112 ] . Active compounds may be flavonoids (quercetin, astragalin), ellagitannins (amarinic acid), hydrolysable tannins (phyllanthisiin D) [ 112 ] . The multiple plant compounds found in Phyllanthus species might help clear up any physiological condition that results in dogs having difficulty following game animals.


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