Example sentences for: anti-inflammatory

How can you use “anti-inflammatory” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It is generally accepted that the hydroxy acid form of statins are potent inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, an enzyme that plays a critical role in cholesterol metabolism, where they block substrate accessibility to HMG-CoA reductase, effectively subverting cholesterol levels of HDL [ 19 20 21 ] . In addition to lowering cholesterol, statins seem to have a number of additional effects, such as the nitric oxide-mediated promotion of new blood vessel growth [ 22 ] , protection against oxidative modification of low-density lipoprotein, as well as anti-inflammatory effects and a reduction in C-reactive protein levels [ 23 ] . All statins limit cholesterol biosynthesis by inhibiting the committed step in the biosynthesis of isoprenoids and sterols [ 24 ] .

  • These investigators discovered that activation of ROCK1 may account for how nonsteroidal anti-inflammatory drugs specify the scissile bond within the APP transmembrane domain that is cleaved by presenilin/γ-secretase to generate the C-terminus of Aβ.

  • Activated protein C, an endogenous plasma serine protease with antithrombotic, profibrinolytic and anti-inflammatory properties [ 1 2 3 ] , is an important modulator of the host systemic response to severe infection [ 1 ] . Recently, recombinant human activated protein C (drotrecogin alfa [activated]) was approved for the treatment of adult patients with severe sepsis.

  • Sulfasalazine is a widely used anti-inflammatory agent in the treatment of Crohn's disease and ulcerative colitis [ 1 2 3 ] . Recent data has demonstrated that SSZ is also safe and effective in the treatment of rheumatoid arthritis and other rheumatological disorders [ 4 5 ] . Sulfasalazine is a dimer composed of 5-aminosalicylic acid linked by an azo bond to sulfapyridine.

  • Since TGF-β1 has anti-inflammatory properties as well as being able to stimulate new matrix synthesis by chondrocytes, it represents a possible therapeutic agent with which to treat pathologies associated with rheumatoid arthritis and osteoarthritis by local gene delivery.


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