Example sentences for: anti-inflammatory

How can you use “anti-inflammatory” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In recent years it has become evident that nonsteroidal anti-inflammatory drugs (NSAIDs) represent a potential class of cancer chemotherapeutic agents.

  • This increase in resistin production is blocked by both aspirin and rosiglitazone, drugs that have dual anti-inflammatory and insulin-sensitizing actions and have been shown to antagonize NF-κB.

  • Insulin sensitizers that have anti-inflammatory properties, including a synthetic PPARγ agonist as well as aspirin, suppress macrophage resistin expression, as does direct inhibition of NF-κB.

  • On the other hand, many synthetic compounds such as the non-steroid anti-inflammatory drugs (NSAIDs) are PPARα and PPARγ agonists [ 27 ] . Since these are agents used clinically for other purposes, it is important to determine whether interaction of these agents with PPARs could modulate atherogenesis in a positive or negative manner.

  • Naturally occurring triterpenoids, such as ursolic acid, have been found to have mild anti-inflammatory effects [ 18 27 ] . These have been improved with the development of synthetic triterpenoids such as CDDO, offering a potential therapeutic tool for the treatment of arthritis and other diseases [ 19 20 21 ] . Furthermore, it has been reported that CDDO at high doses (5-10 μM) can have pro-apoptotic effects, ideal for the treatment of leukemia but of concern with regard to chondrocyte cell death [ 25 26 ] . However, we found that CDDO, at concentrations that decrease MMP-1 and MMP-13 expression (namely 300 nM and 1 μM), did not cause cell death.


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