Words similar to anti-apoptotic
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- anti-apoptotically
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Example sentences for: anti-apoptotic
How can you use “anti-apoptotic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Similarly, inositol 1,4,5-trisphosphate receptors (IP3R) are intracellular calcium release channels involved in diverse signaling pathways and are required for the activation of T lymphocytes [ 33 ] . Tat (also implicated as a neurotoxin) has been shown to release calcium from inositol 1,4, 5-trisphosphate (IP3) receptor-regulated stores in neurons and astrocytes causing premature apoptosis [ 34 ] . Down-regulation of IP3 may therefore contribute to viral latency and maintenance of an anti-apoptotic state in cells.
It was suggested that down-regulation of PS1 by wildtype p53 and also p21 WAF-1may be independent mechanisms leading to apoptosis and tumor suppression [ 24 ] . Our data correlating PS1 with IL-8-tumor related tissue also suggest a potential anti-apoptotic role for PS1 in tumorigenesis.
Mcl-1 is an anti-apoptotic member of the Bcl-2 family whose expression is correlated with decreased apoptosis and increased survival in human neutrophils [ 15 16 ] . Western blot analysis showed that neutrophils from control animals did not express Mcl-1 protein (Fig.
In this way, carboxy- and amino-terminal BRCA1 mutations may target two distinct anti-apoptotic pathways.
In contrast to the pro-apoptotic role for Btk in DT40 cells, Btk appears to play an anti-apoptotic role in mature B cells in vivo . The mechanism may involve Btk-dependent activation of the transcription factor NF-κ B [ 7, 10] and subsequent upregulation of the anti-apoptotic protein Bcl-X L [ 39, 40].
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