Words similar to anti-apoptotic
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Example sentences for: anti-apoptotic
How can you use “anti-apoptotic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Anti-apoptotic genes
TNF-α is a well-characterized, potent inducer of IL-8 transcription and an anti-apoptotic agent [ 30 31 32 ] . Roebuck provides a detailed analysis of IL-8 promoter structure including a promoter recruitment mechanism which involves TNF-α and the cooperativity of NF-kB and NF-IL-6 binding sites [ 4 32 ] . TNF-α exerts many of its effects through TNFR-1 and TNFR-2 receptors, thus co-expression of these receptors with IL-8 might be anticipated.
Injured adult DRG neurons do not die after axonal injury [ 15 ] as a result of the upregulation of cell survival factors such as the small heat shock protein HSP27 [ 16 ] . We now find several genes that could have a survival-promoting role, including the peripheral benzodiazepine receptor, whose agonists are potent antiapoptotic compounds [ 17 ] , GADD45A, which maintains genomic stability and appears to be anti-apoptotic in neurons after ischemic damage [ 18 ] , metallothionein 1L, which is a free radical scavenger [ 19 ] , GTP cyclohydrolase 1, which is obligatory for the actions of NGF on PC12 cells [ 20 ] , and IES-JE (MCP-1) which attracts macrophages, which in turn have been reported to have a role in neuronal survival [ 21 ] .
It was suggested that down-regulation of PS1 by wildtype p53 and also p21 WAF-1may be independent mechanisms leading to apoptosis and tumor suppression [ 24 ] . Our data correlating PS1 with IL-8-tumor related tissue also suggest a potential anti-apoptotic role for PS1 in tumorigenesis.
Mcl-1 is an anti-apoptotic member of the Bcl-2 family whose expression is correlated with decreased apoptosis and increased survival in human neutrophils [ 15 16 ] . Western blot analysis showed that neutrophils from control animals did not express Mcl-1 protein (Fig.
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