Example sentences for: angiostatic

How can you use “angiostatic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The purpose of these experiments was to investigate the response to angiostatic gene therapy of the two selected lung tumours with different characteristics.

  • SLC/CCL21, a CC chemokine expressed in high endothelial venules and in T cell zones of spleen and lymph nodes, strongly attracts naive T cells and DCs [ 1 2 3 4 5 6 7 8 ] . Because DCs are potent APCs that function as principal activators of T cells, the capacity to facilitate the co-localization of both DC and T cells may reverse tumor-mediated immune suppression and orchestrate effective cell-mediated immune responses [ 9 10 25 26 27 ] . In addition to its immunotherapeutic potential, SLC/CCL21 has been found to have potent angiostatic effects [ 28 ] , thus adding further support for its use in cancer therapy.

  • It is also noteworthy that treatment with the endostatin vector, which results in a much higher level of the angiostatic protein (1-3 μg / ml), does not significantly reduce the number of metastases.

  • Other investigators reported that at those concentrations endostatin and ATF induced responses of tumours and metastases in mice [ 31 32 ] . The absence of a response in our tumour model might be due to a lower sensitivity to angiostatic agents.

  • Thus, large tumours that are richly vascularised might be more sensitive to angiostatic therapy.


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