Words similar to angiostatic
Example sentences for: angiostatic
How can you use “angiostatic” in a sentence? Here are some example sentences to help you improve your vocabulary:
SLC/CCL21, a CC chemokine expressed in high endothelial venules and in T cell zones of spleen and lymph nodes, strongly attracts naive T cells and DCs [ 1 2 3 4 5 6 7 8 ] . Because DCs are potent APCs that function as principal activators of T cells, the capacity to facilitate the co-localization of both DC and T cells may reverse tumor-mediated immune suppression and orchestrate effective cell-mediated immune responses [ 9 10 25 26 27 ] . In addition to its immunotherapeutic potential, SLC/CCL21 has been found to have potent angiostatic effects [ 28 ] , thus adding further support for its use in cancer therapy.
Thus, large tumours that are richly vascularised might be more sensitive to angiostatic therapy.
endostatin, angiostatin, thrombospondin) differ in their angiostatic activity from synthetic inhibitors, since they appear to also block endothelial cell proliferation and/or migration.
mhATF-BPTI is a newly designed chimeric protein that has angiostatic properties and endostatin is an angiostatic undergoing clinical trials that was used for comparison.
MIG/CXCL9 and IP-10/CXCL10 are potent angiostatic factors that are induced by IFNγ [ 14 16 17 ] . Both MIG/CXCL9 and IP-10/CXCL10 are chemotactic for stimulated CXCR3-expressing activated T lymphocytes that could further amplify IFNγ at the tumor site [ 30 ] . Hence we postulated that in addition to IFNγ, IP-10/CXCL10 and MIG/CXCL9 would also be important contributors to the tumor reduction in the context of SLC/CCL21 therapy.
Loading...