Words similar to angiostatic
Example sentences for: angiostatic
How can you use “angiostatic” in a sentence? Here are some example sentences to help you improve your vocabulary:
Other investigators reported that at those concentrations endostatin and ATF induced responses of tumours and metastases in mice [ 31 32 ] . The absence of a response in our tumour model might be due to a lower sensitivity to angiostatic agents.
endostatin, angiostatin, thrombospondin) differ in their angiostatic activity from synthetic inhibitors, since they appear to also block endothelial cell proliferation and/or migration.
The purpose of these experiments was to investigate the response to angiostatic gene therapy of the two selected lung tumours with different characteristics.
Systemic and local delivery of an adenovirus encoding ATF have been shown to inhibit the growth of primary tumour implants as well as of tumour metastasis in different animal models [ 18 19 ] . In the ATF-BPTI chimeric protein, ATF has two functions (1) the anti uPA effect with its known angiostatic activity and (2) delivery of BPTI at the tumour site due to over-expression of uPAR on tumour and endothelial cells.
SLC/CCL21, a CC chemokine expressed in high endothelial venules and in T cell zones of spleen and lymph nodes, strongly attracts naive T cells and DCs [ 1 2 3 4 5 6 7 8 ] . Because DCs are potent APCs that function as principal activators of T cells, the capacity to facilitate the co-localization of both DC and T cells may reverse tumor-mediated immune suppression and orchestrate effective cell-mediated immune responses [ 9 10 25 26 27 ] . In addition to its immunotherapeutic potential, SLC/CCL21 has been found to have potent angiostatic effects [ 28 ] , thus adding further support for its use in cancer therapy.
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