Example sentences for: angiostatic

How can you use “angiostatic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • mhATF-BPTI is a newly designed chimeric protein that has angiostatic properties and endostatin is an angiostatic undergoing clinical trials that was used for comparison.

  • Systemic and local delivery of an adenovirus encoding ATF have been shown to inhibit the growth of primary tumour implants as well as of tumour metastasis in different animal models [ 18 19 ] . In the ATF-BPTI chimeric protein, ATF has two functions (1) the anti uPA effect with its known angiostatic activity and (2) delivery of BPTI at the tumour site due to over-expression of uPAR on tumour and endothelial cells.

  • The ED50 of endostatin (1000 ng / ml) was in the range of published data [ 25 ] . Further, the angiostatic and antitumoral activities of the human endostatin has been demonstrated in different rat models [ 26 27 28 ] .

  • endostatin, angiostatin, thrombospondin) differ in their angiostatic activity from synthetic inhibitors, since they appear to also block endothelial cell proliferation and/or migration.

  • Thus, large tumours that are richly vascularised might be more sensitive to angiostatic therapy.

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