Example sentences for: androstenedione

How can you use “androstenedione” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • A number of studies have evaluated possible associations between a polymorphism in the cytochrome P450c17α ( CYP17 ) gene and breast cancer risk [ 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 ] . Cytochrome P450c17α functions at key branch points in human steroidogenesis, catalyzing the ovarian and adrenal biosynthesis pathways for androstenedione, the immediate precursor of testosterone [ 17 ] . Three polymorphisms have been described in this gene: a C → T transition at nucleotide 5471 in intron 6 [ 18 ] , a G → A transition at nucleotide 47 in the 5'-untranslated region promoter [ 19 ] , and a thymidine substitution for cytosine at nucleotide 27 in the 5'-untranslated region promoter that creates a Msp AI recognition site [ 20 ] .

  • A NYT editorial and an op-ed by the paper's Bob Herbert call for Mark McGwire to stop taking androstenedione, for the sake of the kids who watch his every move.

  • In contrast, 4-AP significantly reduced estradiol production by PGC-2 cultures provided with androstenedione (Figure 4B).

  • After 24 h the medium was replaced with serum-free medium containing either pregnenolone (1 μg/ml), androstenedione (100 μM), 5α-dihydrotestosterone (5α-DHT, 10 or 100 μM), or forskolin (5 μM) and IBMX (10 μM).

  • These cells have hormonal receptors capable of converting testosterone and androstenedione into estrone and E 2 by means of aromatase [ 36, 37, 38].


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