Words similar to ampa
Example sentences for: ampa
How can you use “ampa” in a sentence? Here are some example sentences to help you improve your vocabulary:
NMDA, N-methyl-D-aspartate; AMPA, α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; GluR, glutamate receptor; SPM, crude synaptic membrane; CaMKII, calcium/calmodulin-dependent protein kinase II; SDS PAGE, sodium dodecyl sulfate electrophoresis.
The expression of GluR1 is also examined because it is the major functional subunit of the AMPA receptors.
In contrast to previous observations that the AMPA receptor expression is relatively constant in glutamate sensitive neurons [ 26], recent studies have shown that the expression of AMPA receptor subunits, especially GluR1, the major functional subunit of the AMPA receptor [ 11] is regulated developmentally at regional, cellular, and synaptic levels [ 27, 28, 29, 30].
The activation of CaMKII then catalyzes the phosphorylation of AMPA-receptors and enhances AMPA receptor responsiveness [ 37, 39, 40, 60].
Prior to testing our hypothesis experimentally, and determining whether domoic acid had the potential to directly activate rat neonatal microglia in vitro, we thought that it was of critical importance to establish that: (1) the domoic acid preparation used in these experiments was stable, (2) rat neonatal microglia isolated by our methodology expressed the AMPA glutamate receptor GluR4 subunit which has been observed in activated rat microglia in vivo [ 24 ] and, (3) to confirm that the domoic acid concentration selected for our in vitro studies with rat neonatal microglia was one that was clearly toxic to neuronal cells in vitro after a short-term exposure.
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