Words similar to alphoid

Example sentences for: alphoid

How can you use “alphoid” in a sentence? Here are some example sentences to help you improve your vocabulary:

The relatively large sizes of the inserts suggest that genomic alphoid DNA fragments recombine with targeting hooks in the vector by sequences located at DNA fragment ends, rather than by internal sequences.
When centromeric DNA is digested by a restriction endonuclease, the resulting fragments are usually either too small or too large for efficient cloning in bacterial artificial chromosomes [ 22 ] . In recent work we reported isolation of human centromeric DNA using a TAR vector lacking ARS element [ 28 ] . While the isolation was selective, a standard TAR cloning technique does not allow to recover a significant fraction of alphoid DNA arrays that does not contain ARS . In our present study, using the new TAR cloning strategy clones of human alphoid DNA up to ~ 210 kb in length were isolated with high selectivity.
Twenty alphoid DNA-positive clones were further characterized.
The length of centromeric alphoid arrays of different human chromosomes varies from 0.2 to 5 Mb.
Because the human genome contains approximately 250,000 copies of alphoid DNA monomer, it is possible that alphoid DNA could be cloned into an ARS -containing vector even without counter-selection.