Words similar to allosterically

Example sentences for: allosterically

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The amino acid sequences of the Runt domains of all each of the collected genes, together with two previously described sequences from the spider Cupiennius salei [ 15 ] , a sequence from the crayfish Pacifastacus leniusculus , and one from the nematode Meloidogyne hapla , were aligned using Clustal W [ 16 ] , as shown in Figure 2. Functionally, the Runt domain is required both for DNA binding and for interaction with its heterodimeric partner (the beta subunit), which serves to allosterically enhance the DNA binding of the Runt domain [ 1 14 ] . Superposition of the alignment and the known crystal structure of mouse Runx1 [ 14 17 ] reveals that residues that make either direct or indirect contact with DNA are invariant (marked by asterisks in Fig.
In view of the distinct divergence of TrpEb_2 from TrpEb_1, one might expect that either TrpEb_2 has lost the ability to interact allosterically with TrpEa, or perhaps that a divergent subgroup of TrpEa has coevolved with TrpEb_2.