Words similar to allosteric

Example sentences for: allosteric

How can you use “allosteric” in a sentence? Here are some example sentences to help you improve your vocabulary:

Recent results suggest that the C-terminal helix 12 of RXR exerts allosteric effects on RAR function [ 6 ] . However, additional studies suggest that corepressor binding to the apo-RAR component of the heterodimer blocks rexinoid induced binding of coactivators to RXR [ 7 ] . These results suggest that the mechanisms that account for the lack of responsiveness of the non-permissive complexes are complex.
Competing allosteric conformations are mediated by alternative salt bridges between K167 of TrpEb_1 and D305 of TrpEb_1 on the one hand, or between K167 of TrpEb_1 and D56 of TrpEa, on the other.
In addition to the binding sites for natural or endogenous agonists (orthosteric sites), many GPCRs have also been found to have allosteric sites [ 35 ] . These sites can bind natural ligands, as in the case of Zn ions and heparin for the dopamine and neurokinin receptors, respectively, or bind synthetic drugs such gallamine, in the case of the muscarinic receptors [ 35 ] . Binding of small molecules to these allosteric sites can modulate activity of a receptor without directly mimicking or competing out the interaction of ligands to the orthosteric sites.
These putative endogenous Smo modulators could represent orthosteric or allosteric ligands.
Overall, we conclude that binding of both the DNA and the RXR ligands can result in allosteric effects on the function of the CAR/RXR heterodimer.