Example sentences for: allogeneic

How can you use “allogeneic” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Post remission therapy included chemotherapy, allogeneic bone marrow transplantation (BMT) or peripheral stem cell transplantation (PSCT) at the treating physician's discretion and availability of a transplant donor.

  • Frequent infection with herpesviruses has long been recognized in patients undergoing allogeneic transplantation [ 7 8 ] and in patients with acute leukemia [ 1 2 ] . In patients with acute leukemia it has been reported that as many as two thirds of seropositive patients can develop reactivation of herpes simplex virus infection during remission induction therapy [ 26 ] . The risk of CMV infection in acute leukemia patients was recognized almost 30 years ago [ 27 ] but is of particular concern in patients undergoing allogeneic transplantation [ 2 28 ] . EBV infection is frequently associated with post-transplantation lymphoproliferative disorders in T cell-depleted grafts [ 29 ] . As recently reported, HHV-6 can also be associated with bone marrow supression [ 30 ] , encephalitis and pneumonitis [ 7 8 ] after allogeneic transplantation.

  • The incidence of A-GVHD after allogeneic BMT ranges from 30% to 60% with skin as the most commonly affected organ often accompanied by intestinal and / or liver involvement [ 1 2 3 4 ] . Intestinal A-GVHD may manifest as abdominal cramps, ileus, profuse diarrhea, and sometimes bleeding.

  • Of the 13 patients who achieved CR, 6 patients received further consolidation chemotherapy (3 with high dose cytarabine, and 3 with intermediate dose cytarabine combined with daunorubicin, etoposide, or interleukin-2), and 6 patients received either allogeneic BMT or allogeneic PSCT.

  • Acute graft versus host disease (A-GVHD) is a significant cause of morbidity and mortality following allogeneic bone marrow transplantation (BMT).


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