Words similar to all-trans
Example sentences for: all-trans
How can you use “all-trans” in a sentence? Here are some example sentences to help you improve your vocabulary:
The CR-II domain plays an essential role in the ability of TAF II 135 to potentiate ligand-dependent transactivation by the the receptor for all-trans retinoic acid (RAR) in transfected mammalian cells [ 5, 33].
The effects of specific RXR ligands on the CAR/RXR heterodimer have not been characterized, although high concentrations of both 9-cis-RA and all-trans retinoic acid have been reported to block PB induction of the CAR targets CYP2B1 and CYP2B2 in primary rat hepatocytes [ 17 ] . In addition, a recent report suggests that both compounds decrease TCPOBOP-dependent CAR transactivation [ 18 ] . In both cases, these effects were primarily attributed to sequestration of limiting amounts of RXR into ligand-dependent homodimers or heterodimers with other receptors.
In vitro, purified mouse [ 11 ] , human [ 12 ] , and Xenopus [ 13 ] ALDH1A1 can efficiently oxidize all-trans retinal to all-trans retinoic acid.
3shows all-trans RA induced conversion of RAR-α as a function of acid concentration.
The percentage of conversion induced by 1 μM all-trans RA (RARs) or 1 μM 9-cis RA (RXR-β) was used as a positive control to determine the maximum induction.