Words similar to all-trans
Example sentences for: all-trans
How can you use “all-trans” in a sentence? Here are some example sentences to help you improve your vocabulary:
3shows all-trans RA induced conversion of RAR-α as a function of acid concentration.
3and 4also shows that at 200 nM of agonists 1 and 2 , RAR-β exhibits the same activity as the positive control RAR-α induced by all-trans RA at the same concentration.
Exposure to 1 μM all-trans retinal for 96 hours induced differentiation equivalent to exposure to 0.05-0.
The family of retinoic acid receptors includes those that bind only all-trans retinoic acid (RAR α,β,γ and those that bind either all-trans retinoic acid or 9-cis retinoic acid (RXR α,β,γ Since the transcriptional regulation of the retinoic acid ligand/receptor complex appears to involve the binding of receptor heterodimers (RAR/RXR), the specific cellular response may depend on the ratio of all-trans to 9-cis retinoic acid formed, as well as the expression of receptor subtypes.
The HL-60 human promyelocytic leukemia cell line responds in culture to sub-micromolar concentrations of retinoic acid ( all-trans and 13-cis ) by undergoing terminal differentiation to a granulocytic cell with the ability to phagocytose and reduce nitroblue tetrazolium [ 28 ] . The response to retinoic acid in HL-60 cells is dependent on the expression of the retinoic acid receptor RAR α [ 29 ] . The use of all-trans retinoic acid in differentiation therapy for patients with acute promyelocytic leukemia has resulted in prolonged, complete remissions when combined with cytotoxic chemotherapy, and may provide complete, long-term remissions as a single agent [ 30 ] .
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