Words similar to alkoxide
Example sentences for: alkoxide
How can you use “alkoxide” in a sentence? Here are some example sentences to help you improve your vocabulary:
On the basis of observations [ 12 13 ] discussed above, one would expect AppppA with two phosphorothioadenosyl substituents to be a slow substrate with a relatively low K m . However, carbon in place of the β phosphorus (for example in 6b ) would make the leaving group the alkoxide - OCH 2 -CH(OH)-CH 2 O-phosphorothioadenosyl rather than α-thio ATP.
Presumably, because normal Fhit products are mononucleotides with low p K a values, the enzyme does not have a group to protonate an alkoxide leaving group and thus substitution of carbon for the β phosphorus turns a substrate into an inhibitor.